In-Cardiome knowledgebase |
In-Cardiome (Integrated Cardiome Database) is an integrated knowledgebase developed by coherently converging independent datasets into unified platform to create a valuable source for improved clinical and scientific understanding of Coronary Heart Disease / Coronary Artery Disease (CHD/CAD). By integrating 20 different data sources using network of Functional Communicating Ontologies (FCO's) and correlating to Indian Atherosclerosis Research Study (IARS), we have shown association between different risk factors to CAD from molecular level to clinical phenotypes. Furthermore, by incorporating biomarkers, drug-drug target networks and gene expression profiles from animal models and patients, we have provided single unified platform for improved scope of translational research and drug discovery/development in cardiovascular diseases (CVD).